respiratory diseases — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0861	Tylosin tartrate		Antibacterial , Antibiotic
	Tylosin tartrate, a macrolide antibiotic, is approved for the control of mycoplasmosis in poultry.		Antibacterial , Antibiotic
T1003	Tylosin	Fradizine,Tylosin A,Tylosine,Tylocine	Antibacterial , Antibiotic
	Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.		Antibacterial , Antibiotic
T0383	Fenspiride hydrochloride	Fenspiride HCl,Pneumorel,Fluiden,Decaspiride	Adrenergic Receptor , PDE , Histamine Receptor
	Fenspiride hydrochloride (Decaspiride) , an oxazolidinone spiro compound, is a drug used in the therapy of certain respiratory diseases. It is approved for use in Russia for the therapy of chronic and acute inflammatory ...		Adrenergic Receptor , PDE , Histamine Receptor
T0768	Oxolamine citrate	AF-438 citrate,SKF-9976 citrate	Others
	Oxolamine citrate (AF-438 citrate) is a cough suppressant that is able to be used as a generic drug in many jurisdictions.		Others
T67815	Uk-50001		PDE
	uk-50001 is a phosphodiesterase (PDE) 4 inhibitor that can be used for many diseases, especially inflammation, allergies, respiratory diseases, disorders and conditions and wounds.		PDE
T15431	Nemiralisib	GSK2269557 (free base),GSK2269557	PI3K
	Nemiralisib（GSK-2269557 free base） is an orally available, potent and specific PI3Kδ inhibitor with a pKi of 9.9.Nemiralisib is used for the treatment of respiratory diseases including chronic obstructive pulmonary disea...		PI3K
T61239	GAL-021 sulfate		Potassium Channel
	GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases.		Potassium Channel
T21322	Mavelertinib	PF 06747775,PFE-X775,PF-06747775,PF-7775,PF 6747775,PF6747775	EGFR
	Mavelertinib (PF-06747775) is an orally available, selective and potent EGFR tyrosine kinase (EGFR TKI) inhibitor with inhibitory effects on T790M/L858R and T790M/Del, and can be used in the study of oncology and respira...		EGFR
T39719	Nrf2 activator-1	Nrf2 activator-1	Nrf2
	Nrf2 activator-1 is a potent activator of NF-E2-related factor 2 (Nrf2).Nrf2 activator-1 can be used to study COPD and other respiratory diseases including asthma, acute lung injury (ALI), acute respiratory distress synd...		Nrf2
T9653	(E/Z)-Sivopixant	(E/Z)-S-600918	P2X Receptor
	(E/Z)-Sivopixant ((E/Z)-S-600918)is a potent P2X3 receptor antagonist, IC50 = 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research.		P2X Receptor
T60522	Letosteine	Viscotiol	Others
	Letosteine (Viscotiol) is an orally active, effective, and safe expectorant that can be used in the study of acute or chronic respiratory diseases, for example, bronchopulmonary disease. Letosteine dissolves bronchial mu...		Others
T6850L	GSK2292767 FA	GSK2292767 FA(1254036-66-2 Free base)	PI3K
	GSK2292767 FA is a potent and selective inhibitor of PI3Kδ (pIC50 : 10.1).GSK2292767 FA is more than 500-fold more selective than other PI3K isoforms.GSK2292767 FA can be used in the study of respiratory diseases.		PI3K
T68086	Imitrodast		Thrombin
	Imitrodast is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor for the treatment of immune system disorders, respiratory disorders, and cardiovascular diseases, and can be used in studies of arterial th...		Thrombin
T0920	Ambroxol	Ambroxolum,NA-872	P450 , Autophagy
	Ambroxol (NA-872) is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a muco...		P450 , Autophagy
T5623	Bisphenol A		Others , Endogenous Metabolite
	Bisphenol A is an endogenous metabolic compound of phenols and is widely used in the production of epoxy resins and polycarbonate plastics. It is reproductive, developmental and systemic toxicant and is often classified ...		Others , Endogenous Metabolite
T67385	Neratinib maleate	HKI-272 maleate	EGFR , HER
	Neratinib maleate (HKI-272 maleate) is an irreversible, orally active and highly selective inhibitor of HER2 and EGFR with IC50 values of 59 nM and 92 nM, respectively.Neratinib maleate has antitumor activity and can be ...		EGFR , HER
T70402	LAS195319
	LAS195319 is a potent and selective inhaled PI3Kδ Inhibitor (IC50 = 0.5 nM) for the Treatment of Respiratory Diseases.
T39612	BTK-IN-5
	BTK-IN-5 is a covalent inhibitor of Bruton's tyrosine kinase (BTK) designed for the treatment of medical conditions including cardiovascular diseases, respiratory diseases, inflammation, and diabetes.
T10121	Substance P Receptor Antagonist 1		Others
	Substance P Receptor Antagonist 1 has the potential function in gastrointestinal disorders, inflammatory diseases, respiratory, and central nervous system disorders.		Others
T69786	GSK3491943
	GSK3491943 is a potent TRPV4 inhibitor with IC50 = 3.2 nM. GSK3491943 is a potential agent for the treatment of heart failure and respiratory diseases.